Dr. Luisa Guerrini

1989-1992

Assistent Research Scientist, Laboratory of Prof. Claudio Basilico, Department of Pathology, New York University School of Medicine, New York.

1992-1994

Research Assistent, Department of Genetics and Microbiology, University of Milan, Italy (Prof. Francesco Blasi).

November 1994

Assistent Prof., Department of Genetics and Microbiology, University of Milan, Italy.

• Gong S., Guerrini L. and Basilico C. (1991) Regulation of Asparagine Synthetase gene expression by amino acid starvation. Mol. Cell. Biol., 11, 6059- 6066.
• Guerrini L., Gong S., Mangasarian K., and Basilico C. (1993) Cis and trans acting element involved in amino acid regulation of Asparagine Synthetase gene expression. Mol. Cell. Biol., 13, 3202- 3212.
• Hansen S.K., Guerrini L., and Blasi F. (1994) Differential DNA sequence specificity and regulation of HIV-1 enhancer and cellular promoters by the c-Rel-RelA transcription factor. J. Biol. Chem., 269, 22230- 22237.
• Lombardi L., Ciana P., Cappellini C. Trecca D., Guerrini L., Migliazza A., Maiolo A.T.,and Neri A. (1995) Structural and functional characterization of the promoter region of the NFKB2 gene. Nucleic Acids.Res. 23, 2328- 2336.
• Guerrini L., Blasi F. and Denis-Donini S. (1995) Synaptic activation of NF-kB by glutamate in cerebellar granule neurons in vitro. Proc. Natl. Acad.Sci. USA 92, 9077- 9081.
• Reuning U., Wilhelm O., Nishiguchi T, Guerrini L., Blasi F., Graeff H., and Schmitt M. Inhibition of NF-kB-RelA expression by antisense-oligodeoxinucleotide suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PA-1. (1995) Nucleic Acids Res. 23, 3887- 3893.
• Guerrini L., Casalino L., Corti A., and Blasi F. (1996) NF-kB mediated regulation of urokinase gene expression by PMA and TNF-a in human A549 cells. Febs Letters 393, 69- 73.
• Trecca D., Guerrini L., Fracchiolla N. S., Pomati M., Baldini L., Maiolo A.T., and Neri A. (1997) Identification of a tumor-associated mutant form of the NF-kB p65/RelA gene with reduced DNA-binding and transactivating activities. Oncogene, 14: 791- 800.
• Guerrini L., Molteni A., Wirth T., Kistler B. and Blasi F (1997) Glutamate dependent activation of NF-kB during mouse cerebellum development. Journ Neurosci, 17 6057- 6063.
• Guerrini L., C. De Santis, P. Robioni, A. Beretta and Blasi F. (1997) Nuclear levels of NF-kB correlate with syncytium-forming capacity of 8e51 cells, expressing a defective HIV virus. Febs Letters, 214, 277- 280.
• Guerrini L., Molteni A., and Blasi F. Possible stage specific function of NF-kB during B cell differentiation. (Febs Letters, in press).
• Guerrini L., D.Trecca, A. Migliazza, F. BLasi and Neri. A. Characterization of two oncogenic rearrengements of the NFKB2 gene. (Submitted).